Polydioxanone (PDO/PDS) Chemistry
Polydioxanone (PDO, PDS) or poly-p-dioxanone is a colorless, crystalline, biodegradable synthetic polymer. Due to KFDA regulations threads must be made violet.
Polidioxanone (PDO) Benefits
- Uniformity of the caliber
- Handling and poor memory
- Good biological tolerability
- Totally absorbable by hydrolysis
- (begins after 10-15 days, completed in 180 days)
- Reabsorption by lymphatic
- Totally safe
Scientific Logic Behind MEDiTHREAD
Clinical observation showed that PDO (polydioxanone) threads increase the synthesis of endogenous hyaluronic acid and improves local microcirculation. In short, it stimulates production of new collagen protein which results in increased elasticity and firmness of the skin.
Bio-stimulation is a new approach that can lift the face, neck and body. Insertion of the powerful synthetic fiber, consisting of a smooth filament, which is absorbed in the tissue leaves the skin firmer, more elastic and better hydrated.
MEDiTHREAD’s technique of naturally sculpting the face using the tension lines of the skin, causes an effect similar to surgical facelifts. MEDiTHREAD PDO suture limit the strength of the facial muscle and stimulates the effect of botulinum toxin with the advantage that the threads do not paralyze the muscle giving a more natural look.
The effects of using MEDiTHREAD PDO suture as a treatment are: rejuvenation, lifting effect, toning of the tissue, wrinkle improvement, hydrated skin. When using MEDiTHREAD PDO threads, you will see immediate improvements in the appearance of the skin.
After two weeks the body starts synthesis of natural protein of the body (elastin and collagen). Production of natural proteins continues up to 6 months until the PDO thread absorption (hydrolysis) is complete.
Due to the meaningful endogenous stimulation generated by our PDO thread the aesthetic effect can lasts up to 18 months. The time it takes to absorb and the thread diameter prevents the risk of skin thickening and scaring, which is not easy to avoid in other biocompatible materials.
MEDiTHREAD’s PDO / PDS (polydioxanone) suture does not require anesthesia and has a low inflammatory reaction.
PDO is a well-used material for suture in most pediatric cardiac surgery and is a completely safe medical device as well as being completely absorbable and hypoallergenic.
PDO contains no heavy metals and has no significant side effects.